ibusinesslines.com
ibusinesslines.com November 15, 2018


Ground-breaking research finds daily aspirin dose doesn't lead to longer life

18 September 2018, 12:14 | Melissa Porter

According to principal investigator Professor John McNeil, head of Monash University's Department of Epidemiology and Preventive Medicine, the results of the trial will result in a rethinking of global guidelines relating to the use of aspirin to prevent common conditions associated with ageing.

Taking aspirin regularly does not significantly reduce the risk of heart attacks or stroke, a study has found.

'This study shows why it is so important to conduct this type of research, so that we can gain a fuller picture of aspirin's benefits and risks among healthy older persons'.

The findings apply only to older adults who haven't developed a blood-vessel-related problem, however.

In older people, any effect of aspirin on reducing heart disease or stroke might be expected to be enhanced due to their higher underlying risk.

Cardiologist Dr. Erin Michos called the results, "alarming", saying that aspirin should be prescribed only selectively. This has increased the need to resolve whether aspirin in the healthy elderly actually prolongs their good health. Maybe I should take it, even if they haven't really had a heart attack, ' " Murray added. And it had been apparent since the 1990s there was a lack of adequate evidence to support the use of low-dose aspirin in healthy older people.

A total of 19,114 people, mostly over the age of 70, were enrolled in the study. The age limit was lowered for those groups because blacks and Hispanics tend to be younger than whites when they have their first heart attack or stroke.


Another challenge was recruiting the necessary thousands of older volunteers who were healthy and living and often working in their community. Half the participants were asked to take 100mg of aspirin each day, while the rest took a placebo pill. The researchers then followed the study's participants for a median of 4.7 years. Also, the rates of physical disability dementia were similar in both groups.

A daily low-dose aspirin regimen may be doing you more harm than good, it turns out.

While US Preventive Services Task Force guidelines on aspirin use, among other worldwide guidelines, recommend a daily dose to prevent cardiovascular disease between the age of 50 and 69, a lack of available research meant this recommendation was not extended to people older than 70.

"The increase in cancer deaths in study participants in the aspirin group was surprising, given prior studies suggesting aspirin use improved cancer outcomes", Leslie Ford, the associate director of clinical research at the National Cancer Institute's Division of Cancer Prevention, said in a news release. This finding was surprising because nearly half of those extra deaths were due to cancer, including colorectal and other gastrointestinal cancers. But the researchers interpreted the data cautiously, because other studies have shown aspirin to have a protective effect against colorectal cancer.

New seven year long study has found aspirin medication doesn't make seniors live longer.

So what should older healthy adults do with this new information about aspirin?

Extra cases of cancer were the chief reason for the higher death rate, with 3.1 per cent of aspirin users dying of cancer versus 2.3 per cent in the control group.



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