ibusinesslines.com August 17, 2018

Prostate cancer drug extends the lifespan of cancer patients

06 June 2018, 04:31 | Melissa Porter

Image Some men with prostate cancer could live longer thanks to immunotherapy

Some men with prostate cancer could live longer thanks to immunotherapy

Black patients experienced higher rates of several hormonal-based toxicities, such as hyperglycemia, hypokalemia, and hot flashes, "suggesting perhaps a greater exposure risk to this medicine", George said. This is for the first time that an immunotherapy has shown to be beneficial for men who suffer with prostate cancer that is responsible for the death of more people in the United Kingdom than the breast cancer.

This is the first time a trial has shown how immunotherapy can benefit men with prostate cancer, professor Johann de Bono, director of the Drug Development Unit at the Institute of Cancer Research said in a statement.

Further trials will be needed before the drug, already licensed for certain types of skin cancer, lung cancer and lymphoma, is approved for routine clinical use in prostate cancer.

The new trial relates to immunotherapy drugs.

Nell Barrie, from Cancer Research UK, said: "The next step will be to find out how to tell which men will benefit from taking this drug". As a result, the stimulated immune system recognizes and fights the cancer cells present in the body.

A new study conducted by the Institute of cancer research and the Royal Marsden hospital in London has shown awesome results in patients with prostate cancer.

Yes! Now the prostate cancer patients with hardly weeks or months to live will be able to survive longer if they are subjected to proper immunotherapy treatment. Most prostate cancers are slow growing; however, some grow very quickly. While just 5 percent men who were a part of the trail actually saw their cancer to shrink or disappear after receiving the treatment, many of those had heavily mutated cancers.

Professor de Bono said: "We are planning a new clinical trial, specifically in men with prostate cancer whose tumours have mutations in DNA fix genes, to see if immunotherapy can become a standard part of their treatment". As a result, there is insufficient evidence about possible differences in treatment efficacy and side effects by race.

However, the therapy will not work for most patients.

Only around 20% of cancer patients respond to immunotherapy and researchers do not fully understand why. The latest trial, results of which were presented this weekend at the American Society of Clinical Oncology Meeting in Chicago, examined the genetics of tumors and found that certain groups of prostate cancer patients may benefit from the treatment.

Professor Bono concludes, "This new trial has found that testing for mutations in DNA fix genes could be a valuable marker of who will respond".

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