ibusinesslines.com August 19, 2018

Kids, Antibiotics and Kidney Stones

13 May 2018, 03:57 | Melissa Porter

Small children are prescribed antibiotics more than any other group

Small children are prescribed antibiotics more than any other group

Kidney stones have grown much more common over the past few decades without a clear explanation as to why. A new study asserts antibiotics may have had something to do with that.

What's more, after analyzing health records of 13.8 million patients, researchers found that children and adults treated with oral antibiotics have a significantly higher risk of developing kidney stones, marking the first time these treatments have been linked to this condition.

According to Gregory E. Tasian who is a pediatric urologist and the leader of this research, the entire prevalence regarding kidney stones has seen an increase of around 70% in the last 30 years. Tasian noted that kidney stones were previously rare in children.

"We're dealing with a risk-benefit relationship, and we want to make sure that antibiotics are prescribed without unnecessarily increasing adverse health outcomes", he said. After adjustments for age, sex, race, urinary tract infection, other medications and other medical conditions, patients who received sulfa drugs were more than twice as likely as those not exposed to antibiotics to have kidney stones; for broad-spectrum penicillins, the increased risk was 27 percent higher.

Dr. Tasian's findings will appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

They found that five classes of oral antibiotics were associated with a diagnosis of kidney stone disease. Risks were increased 2.3 times, 1.9 times, 1.7 times, 1.7 times, and 1.3-times for sulfas, cephalosporins, fluoroquinolones, nitrofurantoin/methenamine, and broad-spectrum penicillins, respectively.

Drawing on health records from the United Kingdom, the team analysed prior antibiotic exposure for almost 26,000 patients with kidney stones and compared them with almost 260,000 control subjects.

Scientist are already aware that antibiotics alter the composition of the human microbiome, or the community of microorganisms in the body. Just because children are prescribed more of them as compared to adults, researchers suggest that the clinicians need to be more honest and mindful while prescribing medication especially when they are dealing with young patients.

It is still unknown why kidney stones are on a hike these days but according to the study, consuming antibiotics certainly play a major role when it comes to prescribing them to children more than that of adults.

Other News

Trending Now

Brands Are Making Custom Prince Harry and Meghan Markle Swimsuits
Kensington Palace revealed on March 22 that the official invitations for the wedding had been sent to approximately 600 guests. He warned the British prince that he would be making the "biggest mistake in royal wedding history " by marrying Meghan.

Stricker shoots a 73 in round three of Players Championship
I'm sure he was nervous playing that hole. "When you are 14 back on a Saturday morning, there's not a whole lot of pressure". Schwartzel, without a top-25 finish in seven starts at the tournament, showed glimpses of what he is capable of.

Reece Prescod stuns Justin Gatlin to win 100m race in Shanghai
There were further home celebrations after the women's javelin , won by China's Huihui Lyu with a meeting record of 66.85m. Running in the outside lane, the 22-year-old came through to win in 10.04 seconds.

Two killed in bomb attacks on Indonesian churches
El Shinta radio station says the almost-simultaneous attacks occurred when the churches were packed for Sunday morning services. The most serious incident was in January 2016 when four suicide bombers and gunmen attacked a shopping area in central Jakarta.

Dead in Myanmar rebel attacks
The Ta'ang National Liberation Army is one of more than a dozen armed groups that have been fighting the government for more autonomy.

Mother's Day 2018: Gift Ideas, What Presents Most People Spend On
But who looks? It is because people have no idea how to look that they hardly every understand.' I am trying to see my mother . In case your mother is working women, Surprise her at her work, and also you can post a Thank you letter at her work.

Final donation for man whose blood helped save 2.4 million babies
Australia was one of the first countries to discover a blood donor with this antibody, so it was revolutionary at the time. This disease is a condition where a pregnant woman's blood actually starts attacking her unborn baby's blood cells.