The president acknowledged the speculation Tuesday, responding to a question about whether he could beat Winfrey during a bipartisan meeting with senators at the White House.
"I don't think she's going to run", Trump said. "I like Oprah", he added.
Trump has tweeted about Oprah over a dozen times and posted her inspirational messages and quotes.
Beyond her rise from poverty, Winfrey's success as a multidimensional media figure has come from promoting ways for women to assert themselves, typically outside the political arena.
And after some pushing and prodding from her co-anchors, King said she agreed. Her appeal extended well beyond her celebrity, some said, citing her compassion, kindness and devotion to helping others as a badly needed change after Trump.
This isn't the first time Winfrey's presidential run has been shut down.
Kanye West rapped on the phone for dying young fan
The reason we're only hearing about it almost a week later is because a family acquaintance shared on Twitter - Kanye never did. Kim confirmed the touching news by saying "We are praying for her family". "I have so much respect for him tho".
Driver in BMW M5 sets 232.5-mile record for longest drift
And it is these power figures and the corresponding claimed fuel use of 10.5L/100km that cause the headache for BMW's drift aces. That's the length of your typical work day, except the entire time you'd have to be holding a drift in a 600 hp super sedan.
Teacher removed from school board meeting in handcuffs
A teacher in Louisiana was escorted out of a school board meeting in handcuffs after questioning the superintendent's pay. Hargrave also expressed frustration that "performance goals" were cited as a reason Puyau was receiving a reason.
Discovery Communications to move global headquarters to NY
About 1,300 Discovery employees are based in the Silver Spring area, and 1,000 are based at Scripps' Knoxville headquarters. The company's global headquarters was in Bethesda in 1991, before the move to its current location in Silver Spring in 2003.
Amazon CEO Jeff Bezos is world's richest person
Rockefeller was the richest ever, with a net worth of an estimated $340 billion (inflation-adjusted) in 1937. Bill Gates takes a place in the runner-up position with an equally staggering net worth of over $92 billion.
Weather: Mostly sunny, with a high near 32
Friday , freezing rain before 7 a.m., then sleet likely between 7 a.m. and 8 a.m., then snow showers likely after 8 a.m. Some seasonly warm temperatures appear like they will be giving way to several inches of snow starting Wednesday .