ibusinesslines.com August 22, 2017

Scientists unveil a possible new way of healing wounds in the future

08 August 2017, 06:36 | Melissa Porter

TNT technology

Tissue Nanotransfection technology

In less than a week, the technology generated blood vessels ultimately saving the leg. "We are proposing the use of skin as an agricultural land where you can essentially grow any cell of interest", he said. "Our technology keeps the cells in the body under immune surveillance, so immune suppression is not necessary".

It takes just a fraction of a second.

The device is a tiny silicone chip about the size of a dime that "injects genetic code into skin cells, turning those skin cells into other types of cells required for treating diseased conditions", states a release from the university.

"By using our novel nanochip technology, injured or compromised organs can be replaced", explained Dr. Chandan Sen, one of the leaders of the study. "This is hard to imagine, but it is achievable, successfully working about 98 per cent of the time". Mice with badly injured legs that lacked blood flow were healed within three weeks and blood flow was restored.

The Nanotransfection technology is composed of two major components.

TNT is a nanotechnology-based chip created to deliver cargo to adult cells in the body and the design of specific biological cargo for cell conversion.

The team at Ohio State University have successfully trialled TNT on pigs and mice, with a reported success rate of 98 per cent.

This cargo, when delivered using the chip, converts an adult cell from one type to another, said Daniel Gallego-Perez, an assistant professor at Ohio State. A small, barely detectable electric pulse stimulates the existing cells. The process turns the skin into a "bioreactor" to fix damaged tissues.

The US researchers who created the technology say, "It could even be used as a weapon against neurological diseases like Alzheimer's and Parkinson's". Actually, the Researchers managed to grow brain cells on the skin surface of a mouse, harvest them and then inject them into the injured brain of the mouse. In my lab, we have ongoing research trying to understand the mechanism and do even better.

What appeals to you the most about this breakthrough technology, the idea of healing and regrowing damaged body parts or the idea that it can be used to stop aging and prolong life?

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